The Gut-Skin Connection: Your Secret to a Summer Glow

Ever wonder why some people seem to have that effortless, radiant glow while others struggle with skin issues like slow wound healing or excessive wrinkles? The answer might be hiding in your gut! Science is revealing a fascinating connection between our digestive health and skin appearance—and it's changing everything we thought we knew about our skin. 

The Gut-Skin Connection

Just like the gut and brain, think of your gut and skin as best friends who are constantly texting each other. This communication highway, known as the gut-skin axis, means that what's happening in your digestive system directly impacts how your skin looks and feels.1 When your gut is happy and balanced, it shows up as clearer, more radiant skin. But when things go sideways in your digestive tract, your skin often bears the brunt of it.

Here's the science: your gut houses about 70% of your immune system,2 and when harmful bacteria outnumber the good guys, inflammation kicks into overdrive.1 This internal fire doesn't stay put—it travels throughout your body, including to your skin, where it can manifest as breakouts, redness, dullness, or even conditions like eczema and rosacea.1

On the flip side, a well-balanced gut microbiome helps keep inflammation in check, supporting that coveted healthy glow from the inside out.1

The takeaway? That luminous summer or “glass” skin you're after goes deeper than surface-level solutions—it's about nurturing the trillions of beneficial bacteria living in your gut. When you prioritize internal health, external radiance naturally follows.  

Meet L. reuteri (And Why It's So Interesting)

Enter Limosilactobacillus reuteri DSM 17938 – a superstar probiotic strain that's catching scientists' attention for its potential skin benefits. One piece of current research involves topical applications of L. reuteri directly to skin, rather than oral supplementation, so we're still learning how these benefits might translate when taken internally. This research is still emerging, and more studies are needed to fully understand all the mechanisms at play. But the preliminary findings? Pretty exciting. 

Here's what early topical research suggests about L. reuteri DSM 17938's skin-supporting powers:

Sun Protection from Within: This clever little bacterium appears to help your skin cope with UV stress by reducing inflammation caused by UVB rays – you know, the ones responsible for sunburns and potential DNA damage that can lead to skin cancer.3 It works by dialing down concentrations of inflammatory molecules called IL-6 and IL-8, which your skin produces when it's under stress.3

Hydration and Elasticity Boost: L. reuteri DSM 17938 seems to increase expression of the AQP3 gene, which plays a crucial role in skin hydration and elasticity.3 Think of it as your skin's internal moisturizing system getting a natural upgrade.

Anti-Inflammatory Action: This strain also appears to decrease expression of the KLK5 gene, which contributes to skin inflammation.4 Less inflammation typically means calmer, clearer-looking skin.

Pathogen Protection: In laboratory studies, L. reuteri DSM 17938 has shown the ability to inhibit common harmful bacteria that can affect skin health.4 While this hasn't been tested directly on skin yet, it suggests this strain could be a protective ally.

But what about real-world experiences? Zoguri customers are sharing their own skin stories and when it comes to skin, their experiences sound very compelling. 

"I was having such great luck with Zoguri, with my hair, with my gut, with my sleep. I just decided to take it one level up and start putting it on my skin. I started rubbing it on my face and my hands and within months people were saying to me, ‘your face looks great, your skin looks really good. What are you using?’ And all I'm doing is putting Zoguri on it!"
- Lisa, Zoguri Customer

"I read about L. reuteri and how it can help reduce wrinkles and benefit hair, skin, and nails from the inside out. It has been 3 months since I found Zoguri and my nails are growing super-fast. I've also noticed less hair falling out when I wash my hair, my stylist even commented on all the new hair growth. I think it's working! I even put a little on my face at night and I've had several compliments lately on my glowing skin.”
-Allie, Zoguri Customer

Now, to be clear, we’re not suggesting that you start slathering Zoguri on your skin, but we find it encouraging to hear about our customers’ unique individual experiences and what is working for their wellness journeys. While these results may not be typical, and the use of topical application is still being studied, feedback from actual customers helps us better understand the variety of potential benefits people could experience by replenishing their microbiome with L. reuteri

The Supporting Cast: Other Beneficial Strains

L. reuteri might be the star of the show, but every great performance needs a supporting cast. The other strains in Zoguri’s unique blend work synergistically to support overall wellness – and when you feel good from within, that inner vitality shines through your skin.

S. thermophilus: The Anti-Aging Ally This strain has some impressive credentials in the beauty department. Research shows that S. thermophilus can increase skin collagen production – that's the protein that keeps skin firm and plump.5 Studies also found it helps cells recover from UV damage and significantly improves skin moisture, elasticity, and even reduces the depth of crow's feet.5 Not bad for a microscopic organism!

The Classic Duo: L. acidophilus and L. bulgaricus These time-tested strains have been making waves in skin health research. One fascinating study found that supplementing with L. acidophilus and L. bulgaricus led to an 80% improvement across 300 acne patients in just 16 days.6

L. acidophilus specifically shows promise for inflammatory skin conditions.6 Research suggests it can help reduce symptoms of eczema – that uncomfortable condition where skin becomes inflamed, itchy, and painful.7 By supporting immune balance, this strain may help keep inflammatory skin reactions in check.7   

Intriguingly, laboratory research on human skin cells has shown that L. acidophilus may offer additional skin benefits.6 While this wasn't a clinical study and was performed on human skin cells outside of the body, the results suggest this strain could decrease reactive oxygen species (ROS) – those troublesome molecules that contribute to skin aging and pigmentation. The study also found that L. acidophilus helped prevent cell death from UVB exposure, exhibited anti-wrinkle effects by decreasing expression of aging-related genes, and may help regulate melanin production, potentially leading to more even skin tone.6,8

Together, all these different beneficial bacteria work to support your skin in two crucial ways: Maintaining optimal hydration levels and keeping inflammation balanced.1,9 When your skin is well-hydrated and inflammation is under control, you'll be well on your way to that coveted healthy glow. Again, this research is preliminary, and we need more studies, especially clinical trials, to better understand the benefits for the human body.

Action Plan: Getting Your Event-Ready Glow

Ready to harness the power of the gut-skin connection for your most radiant summer skin yet? Here's your science-backed action plan:      

Anti-Inflammatory Foods

Nourish with Anti-Inflammatory Foods Load up on colorful fruits and vegetables, omega-3 rich fish, nuts, and seeds. These foods provide antioxidants and healthy fats that support both gut and skin health. Think berries, leafy greens, salmon, walnuts, and avocados – basically, nature's beauty foods.

Hydration tips

Hydrate Like It's Your Job Your skin is made up of about 64% water, making proper hydration essential for maintaining its plump, dewy appearance.9 Aim for at least 8 glasses of water daily, and remember that water-rich foods like cucumber, watermelon, and tomatoes count too.


Microbiome support

Support Your Microbiome Here's where strategic probiotic supplementation comes in. Supporting your gut means supporting your skin – it's really that connected! If you're looking for a comprehensive approach, consider a multi-strain blend that includes some of the strains we've explored. Psst... if you're curious about a delicious, fermented yogurt-based option that happens to contain ALL of the beneficial bacteria mentioned here, we invite you to try Zoguri, a 7-strain blend (L. reuteri DSM 17938, L. reuteri ATCC 6475, L. bulgaricus, L. acidophilus, Bifidus, L. casei, and S. thermophilus).

Master the Lifestyle Basics Don't underestimate the power of quality sleep (7-9 hours nightly), stress management through activities like yoga or meditation, and consistent sun protection. These factors all influence both gut health and skin appearance.

Remember, achieving that healthy summer glow isn't about quick fixes – it's about supporting your body's natural systems from the inside out. When you nurture your gut microbiome with the right nutrients and beneficial bacteria, your skin often rewards you with that radiant, healthy appearance you've been seeking. No matter how you incorporate beneficial bacteria into your wellness plan, we think it’s worth a try if obtaining a gorgeous summer glow is on your to-do list this year. Your most luminous skin might just be a few spoonfuls away!

 

1 Villena, Julio, et al. “The Role of Intestinal Microbiota in the Development and Pathophysiology of Skin Diseases.” Microorganisms, vol. 10, no. 7, 2022, article 1411. National Center for Biotechnology Information.
2 Wiertsema, Selma P., et al. “The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies.Nutrients, vol.13, no.3, 9 Mar. 2021, p.886, doi:10.3390/nu13030886. PubMed Central, . Accessed 17 June 2025.
3 Khmaladze I, Butler É, Fabre S, Gillbro JM. “Lactobacillus reuteri DSM 17938-A comparative study on the effect of probiotics and lysates on human skin.” Exp Dermatol. 2019 Jul;28(7):822-828. doi: 10.1111/exd.13950. Epub 2019 May 15. PMID: 31021014.
4 Khan, Reem, and Vaibhav Srivastava. “Effect of Lactobacillus reuteri on Pediatric Acne Vulgaris: Current Evidence and Mechanisms.” Clinical and Medical Journal, vol. 6, no. 8, 2024, pp. 150–155.
5 Vongsa, Rithy, et al. “Efficacy of a Probiotic Skin Care Product on the Improvement of Skin Moisture, Elasticity, and Reduction of Wrinkle Depth.” Journal of Cosmetic Dermatology, vol. 21, no. 2, 2022, pp. 661–667.
6 Probiotics for Skin? Here’s What the Science Actually Says.” Simple Skincare Science, 2021.
7 Kim, Ji Yeun et al. “Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double-blind, randomized, placebo-controlled trial.Pediatric allergy and immunology: official publication of the European Society of Pediatric Allergy and Immunology vol. 21,2 Pt 2 (2010): e386-93. doi:10.1111/j.1399-3038.2009.00958.x  
8 Lim, Hye Yeon et al. “Antiwrinkle and Antimelanogenesis Effects of   Tyndallized Lactobacillus acidophilus KCCM12625P.” International journal of molecular sciences vol. 21,5 1620. 27 Feb. 2020, doi:10.3390/ijms21051620 
9 U.S. Geological Survey. “Water Content of the Human Body.” USGS Water Science School.
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